Phage International, Inc.

BREAKING NEWS

Phage Therapy May Help Fight Resistant Bacteria - CBS News, January 25, 2007

Antibiotic Resistance - KQED Radio, January 20, 2005
Why there are so few new antibiotics in the pharmaceutical pipeline; the potential health crisis that looms ahead.

Phage Therapy Center Georgia is accepting patients with diabetic foot ulcers, tropic ulcers, bed sores, and osteomyelitis -- including those with drug-resistant VRE, Pseudomonas, Klebsiella, Proteus, and MRSA infections.

Eastern European findings on the use of phages to treat conditions such as diabetic ulcers and osteomyelitis, in which poor circulation can render antibiotics toothless, are particularly impressive and incontrovertible. They have excellent cure rates.
-- Science Magazine, October, 2002

A nearly forgotten therapy may yet reemerge as a savior to this accellerating crisis of antibiotic resistance, one that has its roots in Stalin's Russia, but which flourished briefly in the West. Growing levels of antibiotic resistance and the exit of major pharmaceutical companies from antibiotic development means that physicians may one day have no choice but to adopt phage therapy for a growing number of otherwise untreatable infections. -- Nature Biotechnology, January, 2004

Someday, people may look back on the 20th and 21st centuries with nostalgia, as the time when it was possible to treat bacterial infections. With antibiotic resistance on the rise, many antibiotics could be nearly useless in a few generations. -- US News, December 2, 2004

Phage therapy predated antibiotics by decades, but was largely supplanted when antibiotics became available. Now, however, the emerging threat posed by antibiotic-resistant pathogens is spurring a resurgence of interest in phage, as a potential therapy to cure or prevent infections, and as a tool to kill food-borne pathogens.
-- Journal of the American Medical Association (JAMA), Dec, 2003

Resistance is a big problem and growing. You're dealing with living microbes that have shown an incredible ability to accommodate antibiotics and come out winning. We have no idea what they are going to do next. Our fear is that we're seeing the tip of the iceberg. -- US Food and Drug Administration

Along with the excitement of a new approach to antibacterial therapy, at a time when many antibiotics have run out, should be a renascence of study of bacteriophages as smaller fleas on their bacterial hosts in nature. Better hints as to the utility of phage in therapy might come from observations of the natural history of bacterial infections where phage might play a role, a subject scarcely mentioned since d'Herelle's time.
-- Joshua Lederberg, Nobel Laureate, Proceedings of the National Academy of Sciences, 1996

Whenever a newspaper obituary lists cause of death as "complications" following surgery, chances were that a doctor guessed wrong in terms of antibiotics -- or the bug had proved resistant to all of them. This was code that all healthcare workers, hospital staff, and HMO providers understood but few outside the medical world knew.
-- Michael Shnayerson and Mark Plotkin, "The Killers Within"